HIGHLIGHTS
- who: Tae Hyung Won from the (UNIVERSITY) have published the paper: Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi, in the Journal: (JOURNAL) of 29/07/2022
- what: The authors show, using untargeted comparative metabolomics, that CrmA generates a valine-derived isocyanide that contributes to two distinct biosynthetic pathways under copper-limiting conditions. The study shows that this approach can enable major advances in understanding fungal secondary_metabolism, including genuinely new biosynthetic pathways and small-molecule functions.
- how: The authors used mixed cultures of A. fumigatus u0394crmA which produces . . .
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