Coronin7 regulates wasp and scar through crib mediated interaction with rac proteins

HIGHLIGHTS

• who: Karthic Swaminathan from the Center for BiochemistryUniversity of have published the research: Coronin7 regulates WASP and SCAR through CRIB mediated interaction with Rac proteins, in the Journal: Scientific Reports Scientific Reports
• what: The authors focused first on Rac effectors that play a key role in phagocytosis. Next, the authors focused on SCAR, a known positive regulator of actin polymerization.

SUMMARY

The authors expressed several of them as GST-fusion_proteins, preloaded them with GDP or GTPγ S and used them to pull down GFP-tagged CRN7 from cell lysates and probed . . .

 



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