Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences

HIGHLIGHTS

• who: Andonis Gerardos et al. from the Institute of Bioengineering, School of Life Sciences, Eu0301cole Polytechnique Fu00e9du00e9rale de (EPFL), Switzerland, SIB Swiss Institute of Bioinformatics, Switzerland have published the Article: Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences, in the Journal: (JOURNAL) of May/16,/2022
• what: The authors show that correlations from these two sources combine constructively to increase the performance of partner inference by DCA or MI. While these phylogenetic correlations are known to obscure the inference of structural contacts the authors show using controlled synthetic . . .
  

   

  

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