Cortical synaptic transmission and plasticity in acute liver failure are decreased by presynaptic events

HIGHLIGHTS

  • who: Mariusz Popek from the Department of Neurotoxicology, Mossakowski Medical Research Centre, Polish Academy of Sciences, PawiƄskiego , St, Warsaw, Poland have published the paper: Cortical Synaptic Transmission and Plasticity in Acute Liver Failure Are Decreased by Presynaptic Events, in the Journal: (JOURNAL)
  • what: This study provided an exhaustive description of alterations in synaptic transmission, ultrastructure, and expression of synaptic transmission-related proteins in the frontal cortex of mice with ALF. Impairment of LTP has been repeatedly demonstrated in chronic liver failure , the studies mostly focusing on the role of modulation of the NMDA-sGCnNOS . . .

     

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