Coup-tfi modifies cxcl12 and cxcr4 expression by activating egf signaling and stimulates breast cancer cell migration

HIGHLIGHTS

  • who: INSERM U and collaborators from the Institut de Recherche en Santé-Environnement-Travail (IRSET), Université de Rennes, Equipe TREC, Biosit, Rennes, France, University of Rennes, Beaulieu Campus, have published the paper: COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration, in the Journal: (JOURNAL)
  • what: The authors report that the CXCL12/CXCR4 signaling pathway a crucial pathway in cell growth and migration is an endogenous target of in breast cells. The authors provide evidence that these effects of increase the growth and motility of MCF-7 . . .

     

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