Covalent flavinylation is essential for efficient redox catalysis in vanillyl-alcohol oxidase*

HIGHLIGHTS

  • who: Marco W. Fraaije from the (UNIVERSITY) have published the paper: Covalent Flavinylation Is Essential for Efficient Redox Catalysis in Vanillyl-alcohol Oxidase*, in the Journal: (JOURNAL) of July/16,/1999
  • how: From the results described in this study it can be concluded that this proposed self-protecting function of covalent flavinylation is not generally valid.

SUMMARY

    Redox potentials of both wild_type and H422A vanillylalcohol oxidase have been determined. Reduction of wild_type enzyme did not result in any formation of flavin semiquinone and revealed a remarkably high redox potential of 155 . . .

     

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