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SUMMARY
The first utilized was Frontiers in Immunology | www.frontiersin.org July 2022 | Volume 13 | Article 872683 COVID-19 Immunization-related Autoimmune Adverse Events vitro transcribed (IVT) mRNA in animals was described, when reporter gene mRNAs were injected into mice and protein synthesis was detected. This finding did not lead to an increase in the mRNA_vaccine investment, due to concerns regarding mRNA instability, inefficient in_vivo delivery, and high innate immunogenicity. Subsequently, over the past decade, the use of mRNA_vaccines has been gradually implemented due to their low potential risk of infection and insertional mutagenesis. Actually . . .
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