HIGHLIGHTS
- who: Marina Fuertes-Agudo and collaborators from the Instituto de Biomedicina de Valencia (IBV), CSIC, Jaume Roig, Valencia, Spain have published the research: COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury, in the Journal: Antioxidants 2022, 1724 of /2022/
- what: Using genetically modified mice expressing human COX-2 (h-COX-2 Tg) specifically in hepatocytes and performing I/R surgery on the liver the authors demonstrate that COX-2 expression has a beneficial effect at the mitochondrial level. Considering the protective effect of hepatic COX-2 induction and the subsequent . . .
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