HIGHLIGHTS
- who: Raghuraj Parihar and colleagues from the of Chemistry, College, Kota, Rajasthan, India have published the Article: CP-MLR/PLS directed quantitative structure-activity relationship study on the CDK8 inhibitory activity: The derivatives of naphthyridine and isoquinoline, in the Journal: (JOURNAL)
- what: The CDK8 and 7dF3 inhibition activity of naphthyridine and isoquinoline derivatives have been quantitatively analyzed in terms of Dragon descriptors.
SUMMARY
The pivotal role played by cyclin-dependent kinases (CDKs) in the regulation of cell progression and gene transcription puts these as promising therapeutic targets for various diseases. To . . .
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