Craniofacial defects in embryos with homozygous deletion of eftud2 in their neural crest cells are not rescued by trp53 deletion

HIGHLIGHTS

• who: Marie-Claude Beauchamp and colleagues from the Research Institute, McGill University Health Centre, Glen Site, Montreal, QC H A , Canada have published the research work: Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion, in the Journal: (JOURNAL)
• what: The authors show that P53 level and activity are reduced in Eftud2ncc-/- embryos that were treated with pifithrin-u03b1. The study shows that craniofacial malformations and death of Eftud2ncc-/- mutant embryos are independent of P53-activation. More specifically, the authors show that Eftud2ncc-/- mutant . . .
  

   

  

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