Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting

HIGHLIGHTS

  • who: . et al. from the Jiangsu University, China have published the article: Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting, in the Journal: (JOURNAL)
  • what: The study provided experimental evidence showing the therapeutic potential of creatine for the treatment of cachexia-associated weight loss and muscle atrophy. The study showed that creatine supplementation can inhibit the activation of UPS and ALP in skeletal muscle by activating the Akt signaling pathway, increase the creatine content in skeletal muscle, and provide ATP to skeletal muscle. The authors propose that this observation might . . .

     

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