Creatine supplementation strategies aimed at acutely increasing and maintaining skeletal muscle total creatine content in healthy, young volunteers

HIGHLIGHTS

• What: Although interventions were administered by oral gavage to minimize any impact of palatability on end-point measures, this study demonstrated that combining more tolerable quantities of carbohydrate and protein with relatively small quantities of insulin potentiating amino_acids (leucine and phenylalanine) augmented whole body Cr retention above that seen with Cr alone in healthy, young volunteers over 3 days. The authors aimed to quantify the impact of acute and longerterm Cr supplementation on muscle Cr transporter mRNA expression given the limited published data available. Of note, the insight this research aims to deliver is of importance from . . .
  

   

  

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