Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system

HIGHLIGHTS

• who: Amanda Bas-Cristu00f3bal Menu00e9ndez from the DivisionErasmus University have published the research work: Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system, in the Journal: Scientific Reports Scientific Reports
• what: This work shows that fluidic flow acts as a key cue in vascular structure development in kidney organoids, and hypothesizes that the unidirectional flow establishes a VEGF gradient throughout the tissue that gives directionality and polarization to support EC u00adgrowth9. Thereby, in this study the authors aimed to achieve endothelial ingrowth inside kidney organoids via co-culture with synthetic . . .
  

   

  

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