HIGHLIGHTS
- who: CD et al. from the Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, Zurich, Switzerland have published the article: CRISPR/Cas9-mediated abrogation of CD95L/CD95 signaling-induced glioma cell growth and increases survival in murine glioma models, in the Journal: (JOURNAL)
- what: The authors explored comprehensively the role of cancer cell-intrinsic and tumor microenvironment-mediated CD95L/CD95 interactions using syngeneic mouse glioma models. To ensure the study of constitutive CD95 signaling without artifacts, specific gene deletion of Cd95 and Cd95l was utilized here to elucidate the role of CD95 . . .
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