Crispr/cas9-mediated enrichment coupled to nanopore sequencing provides a valuable tool for the precise reconstruction of large genomic target regions

HIGHLIGHTS

  • who: Giulia Lopatriello et al. from the Department of Biotechnology, University of Verona, Strada Le Grazie, Verona, Italy have published the research: CRISPR/Cas9-Mediated Enrichment Coupled to Nanopore Sequencing Provides a Valuable Tool for the Precise Reconstruction of Large Genomic Target Regions, in the Journal: (JOURNAL)
  • what: The identification of genetic variants underlying phenotypic diversity in plants is central to many studies focusing on conservation and evolution, as well as pre-breeding programs for crop improvement. The authors demonstrate that Cas9 tiling is a valuable, reliable and cost-effective alternative to traditional de novo . . .

     

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