HIGHLIGHTS
- who: Masayuki Tanaka from the Support Center for Medical, u20111193, Japan have published the paper: CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice, in the Journal: (JOURNAL)
- what: The authors develop (CRISPR-Knock-ins and Inserts Searching PRotocol) a to identify both lesions and insertions. uses as little as 3.4 u03bcg of genomic DNA; thus it can be easily incorporated as an additional step to genotype founder animals for further breeding. The authors show that a modified version of CIRCLE-seq . . .
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