Crispr-mediated activation of α v integrin subtypes promotes neuronal differentiation of neuroblastoma neuro2a cells

HIGHLIGHTS

• who: Integrin Subtypes Promotes Neuronal and collaborators from the Department of Life Sciences, University of Trieste, Trieste, Italy, Department of Experimental Medicine, University of Genoa have published the research: CRISPR-Mediated Activation of u03b1 V Integrin Subtypes Promotes Neuronal Differentiation of Neuroblastoma Neuro2a Cells, in the Journal: (JOURNAL)
• what: The authors investigate how enhancing the expression levels of two major u03b1V integrin subunits (u03b1V and u03b23) regulates neurite outgrowth and branching in an in_vitro model of neuronal differentiation, the neuroblastoma Neuro2a (N2a) cell line. By combining the CRISPR activation (CRISPRa) technology, which relies on a . . .
  

   

  

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