HIGHLIGHTS
- who: Ryan D. Molony from the Institut National de la Santéet de la France have published the paper: CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responses, in the Journal: (JOURNAL)
- how: To determine whether the mechanisms whereby CD4+ T_cells were able to support CD8+ T_cell responses in a repeat challenge assay were contact dependent the authors conducted a Transwell experiment in which CD4 and CD8 T_cells from a given healthy donor were used in a repeat challenge assay in which direct contact between these two cell types was not possible . . .
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