HIGHLIGHTS
- who: Alexander Gillis from the University of Sydney, NSW, Australia have published the research: Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor, in the Journal: (JOURNAL)
- future: Studies are required to connect specific signaling profiles to behavioral effects. Future studies linking in_vitro signaling events to in_vivo behavior would benefit from physiological experiments across species including rodents and non-human primates because MOPr agonist effects including antinociception and lethality vary substantially from the most common model species mice to other rodents and to primates.
SUMMARY
To date, however, the . . .
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