HIGHLIGHTS
- who: William R. P. Denault and colleagues from the Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Centre have published the research work: Cross-fitted instrument: A blueprint for one-sample Mendelian randomization, in the Journal: (JOURNAL) of August/29,/2022
- what: The authors show that even when using weak instruments CFMR is at worst biased towards the null which makes it conservative one-sample MR approach. The approach enables cross-ethnic instrumental variable regression to account for heterogeneity in multi-ethnic sample and is also well-adapted to metaanalysis . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.