HIGHLIGHTS
- who: Kitaik, Lee and Francis J., O`Reilly from the Center for Structural have published the research: Cross-linking mass spectrometry for mapping protein complex topologies in situ, in the Journal: (JOURNAL) of 29/03/2023
- what: As we have discussed, while cross-linking MS for purified complexes is an established technology for deriving residue-residue distances, it is a much more difficult proposition to use it to map protein interactions in intact cells.
SUMMARY
Cross-linking mass spectrometry (cross-linking MS) is one technique that has the potential to bridge . . .
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