Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis

HIGHLIGHTS

• who: Eleni Frangou ‍ ‍ et al. from the Patients and healthy individuals Patients with SLE (n=261) who met the SLICC , or EULAR/ ACR , classification criteria and age-­ matched and sex-­ matched healthy individuals (n=106) were recruited from the Departments of Rheumatology and Nephrology at the University Hospitals of Heraklio, ‘Attikon' University Hospital and the respective Blood Transfusion UnitsActive LN was defined by the presence of proteinuria more than, ., g/day and active urine sediment. A kidney biopsy was performed in all patients with evidence of active kidney disease. Patients either developed active LN de novo or . . .
  

   

  

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