Crosstalk between the cbm complex/nf- b and mapk/ p27 signaling pathways of regulatory t cells contributes to the tumor microenvironment

HIGHLIGHTS

• who: CARMA and collaborators from the Shandong University, China have published the paper: Crosstalk between the CBM complex/NF- B and MAPK/ P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment, in the Journal: (JOURNAL)
• what: The authors provide a brief review of signaling pathways in Tregs and the formation of the TME .

SUMMARY

Some studies have shown that HIF-1α positively affects the function of Tregs and plays a role in their suppressive function in tumors (Clambey et_al, 2012; Westendorf et_al, 2017). PD-1 and PD-L1 . . .

 



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