Crucial role of central nervous system as a viral anatomical compartment for hiv-1 infection

HIGHLIGHTS

  • who: Ana Borrajo and colleagues from the Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy have published the paper: Crucial Role of Central Nervous System as a Viral Anatomical Compartment for HIV-1 Infection, in the Journal: Microorganisms 2021, 9, 2537. of /2021/
  • what: After this study, it was investigated whether Tat was toxic to fetal neurons cultures through a calcium-dependent process or by raising oxidative stress. Principally, this study reported that TRIM5u03b1 is functional in CD4+ T_cells and is dependent on IFNu03b1 and stimulation of the immunoproteasome. The studies explored . . .

     

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