Cruciform dna structures act as legible templates for accelerating homologous recombination in transgenic animals

HIGHLIGHTS

  • who: Huan Ou-Yang et al. from the Program in Translational Medicine, Department of Life Sciences, National Chung Hsing University, Taipei, Taiwan have published the paper: Cruciform DNA Structures Act as Legible Templates for Accelerating Homologous Recombination in Transgenic Animals, in the Journal: (JOURNAL)
  • what: This study examined whether exogenous integration into the chromosomes of transgenic animals was related to structures. This study hypothesized that the stability of dsDNA with cruciform structures was a factor in template alleles for DNA repair mechanisms. This study provides three main findings: (a)
  • how: According to the . . .

     

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