HIGHLIGHTS
- who: Grace I. Hallinan from the Center for Proteome Analysis and Center for Computational and, Indiana University School have published the article: Cryo-EM structures of prion protein filaments from Gerstmann-Sträussler-Scheinker disease, in the Journal: (JOURNAL)
- what: The authors report that in GSS (F198S) APrP filaments are composed of dimeric trimeric and tetrameric left-handed protofilaments with their protomers sharing a common protein fold. The authors determine for the first time the high-resolution cryo-EM structures of human APrP isolated post-mortem from the brain of two GSS (F198S) patients. The . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.