Cryptosporidium parvum subverts antimicrobial activity of cramp by reducing its expression in neonatal mice

HIGHLIGHTS

• who: William Guesdon and colleagues from the (UNIVERSITY) have published the Article: Cryptosporidium parvum Subverts Antimicrobial Activity of CRAMP by Reducing Its Expression in Neonatal Mice, in the Journal: Microorganisms 2020, 8, x FOR PEER REVIEW of /2020/
• what: The authors investigated the role of CRAMP during cryptosporidiosis in neonates. The authors explored the possible effects of the murine cathelicidin CRAMP both in_vitro and in_vivo in the neonatal mouse model. This study shows that CRAMP not only directly inhibits C. parvum viability, but also reduces C. parvum infection when administered to neonatal mice.
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