Cryptosporidium uses cspv1 to activate host type i interferon and attenuate antiparasitic defenses

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  • who: Silu Deng from the Effects of anti-viral reagents and anti-parasite drugs on Cparvum infection of intestinal epithelium Consistent with the results from previous studies41, a small but significant decrease in the infection burden was detected in cultured human intestinal epithelial , cells treated with the antiviral reagents, Indinavir or Ribavirin (Fig., a). Cells were first exposed to C. parvum infection for , h (for parasite attachment and invasion)16, and then exposed to Indinavir or Ribavirin for additional , h followed by measurement of infection burden. Antiparasitic reagent paromomycin was used as the positive control41. A further . . .

     

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