Crystal structure of the human polϵ b-subunit in complex with the c-terminal domain of the catalytic subunit

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  • who: Andrey G. Baranovskiy from the (UNIVERSITY) have published the Article: Crystal structure of the human Polϵ B-subunit in complex with the C-terminal domain of the catalytic subunit, in the Journal: (JOURNAL) of April/24,/2017
  • what: This work provides a structural basis to explain biochemical and genetic data on the importance of B-subunit integrity in replisome function in_vivo. The authors report the crystallization, structure determination, and comparative structural analysis of the full-length human Pol⑀ B-subunit (p59) in complex with the CTD of the catalytic subunit (p261C). The authors propose . . .

     

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