Ct-m8 mice: a new mouse model demonstrates that basophils have a nonredundant role in lupus-like disease development

HIGHLIGHTS

  • who: John Tchen from the University College Hong Kong SAR, China have published the research work: CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development, in the Journal: (JOURNAL)
  • what: The authors report the generation of a new mouse model called CT-M8 (Mcpt8tm1Ics) that allows the expression of the CRE recombinase (CRE) and the tandem Tomato (tdT) fluorescent protein downstream of the gene of the basophil-specific protease mast cell protease 8 (Mcpt8) . The authors aimed at developing a basophil-specific mouse model in . . .

     

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