Cul3 and the btb adaptor insomniac are key regulators of sleep homeostasis and a dopamine arousal pathway in drosophila

HIGHLIGHTS

  • who: Cory, Pfeiffenberger and Ravi, Allada from the Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America have published the article: Cul3 and the BTB Adaptor Insomniac Are Key Regulators of Sleep Homeostasis and a Dopamine Arousal Pathway in Drosophila, in the Journal: (JOURNAL) of August/15,/2012
  • what: The authors report the result of a reverse-genetics approach aimed at identifying regulators of sleep and arousal in Drosophila. The authors focused on the gene with the most robust phenotype, insomniac (inc), a target identifier for the E3 ubiquitin ligase Cullin-3 (Cul3 . . .

     

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