Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types

HIGHLIGHTS

  • who: Ha-Young Seo from the Cancer Research Institute National University have published the Article: Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types, in the Journal: Scientific Reports Scientific Reports
  • what: The authors present 28 MPE-derived lung cancer cell lines and two crizotinib resistant sublines that were comprehensively characterized in accordance with multiple drug responses. The study has demonstrated that MPE-derived NSCLC cell lines also retain the transcriptional characteristics of EGFR-mutant NSCLC, which were distinctive to NSCLC cell lines with other driver mutations such . . .

     

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