Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis

HIGHLIGHTS

  • who: Yan Qin from the Department of Health Management, The Peopleu2019s Hospital of Guangxi Peopleu2019s Republic of China Surgery, Guangxi Medical University Cancer Hospital, Nanning, Peopleu2019s have published the Article: Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis, in the Journal: (JOURNAL)
  • what: The authors comprehensively analyzed the expression difference gene variation and methylation modification of cuproptosisrelated genes (CRGs) in pan-cancer. The study shows that CRGs were significantly expressed in a variety of tumors and CDKN2A had the highest mutation frequency (49%) in all tumors.
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