HIGHLIGHTS
- who: Chen Xiong from the Fudan University, Shanghai, China have published the paper: Cuproptosis: p53-regulated metabolic cell death?, in the Journal: (JOURNAL) of 22/09/2022
SUMMARY
Among them, FDX1 encodes a reductase that converts Cu2+ to Cu+ which is a more cytotoxic form of copper; LIPT1, LIAS, and DLD encode the components of the lipoic_acid pathway; and DLAT, PDHA1, and PDHB encode the lipoylated components of the pyruvate dehydrogenase (PDH) complex, suggesting that the lipoic_acid pathway and protein lipoylation may be important for cuproptosis. How do energy metabolic pathways, such as . . .
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