Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements

HIGHLIGHTS

  • who: Chae-Ok Yun from the Queen Mary University of London, United Kingdom have published the article: Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements, in the Journal: (JOURNAL)
  • what: The authors explore the emergence and evolution of these OVs in preclinical and clinical landscapes and their role in advancement and understanding of IO. Although the main mechanism of synergism during combination therapy using oHSVs and radiation remains elusive, this approach has been evaluated in phase I/II clinical trials . For chemotherapy component of the trial, 5-fluorocytosine (5 . . .

     

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