Current development status of mek inhibitors

HIGHLIGHTS

  • who: Ying Cheng and Hongqi Tian from the Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine have published the research work: Current Development Status of MEK Inhibitors, in the Journal: (JOURNAL)
  • what: The study showed that selumetinib had promising antitumor activity in children with low-grade glioma. A randomized phase III, open label, multicenter, two-arm study was designed to compare the efficacy of binimetinib versus dacarbazine in patients with advanced unresectable or metastatic NRAS mutation-positive melanoma (NCT01763164). In vivo, the study showed that the combination of SL327 . . .

     

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