Current evidence for a role of the kynurenine pathway of tryptophan metabolism in multiple sclerosis

HIGHLIGHTS

• who: Bruce J. Brew from the Research, Sydney, NSW, Australia, Faculty of Medicine, St Vincent's Clinical School, University of New South Wales, Sydney have published the Article: Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis, in the Journal: (JOURNAL) of 30/01/2016
• what: In this review, the authors focus on evidence accumulated from MS studies that have demonstrated a dysregulation of the KP, resulting in elevated levels of neurotoxic metabolites both in the plasma and brain parenchyma (detected in CSF), and thus contribute to the progression . . .
  

   

  

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