HIGHLIGHTS
SUMMARY
Laser treatment for DME was established as the standard of care for nearly 30 years when the Early Treatment of Diabetic Retinopathy Study (ETDRS) was published in 1985. Anti-VEGF therapy in DME has shown superior visual acuity results and acceptable risks compared to focal or macular grid laser, and has also led to the observation that PDR lesions can be reversed during treatment. It was therefore clear that a more successful treatment for DME and PDR was needed, and different treatment alternatives for both diabetic retinal complications should be considered. Anti-VEGF molecules . . .

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