Current understanding of ddx41 mutations in myeloid neoplasms

HIGHLIGHTS

  • who: Kunhwa Kim and collaborators from the Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA have published the research work: Current Understanding of DDX41 Mutations in Myeloid Neoplasms, in the Journal: Cancers 2023, 15, 344. of 23/Dec/2022
  • what: The study showed pathogenic variants of DDX41 mutations resulted in the accumulation of double-strand breaks in human hematopoietic stem_cells causing inflammatory responses.
  • future: Despite the rapid advancements in this field there still is a gap in knowledge that future studies need to address for patients with . . .

     

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