Curse and blessing: upregulation of oncogenes upon treatment with hypomethylating agents in myelodysplastic syndrome

HIGHLIGHTS

  • who: Juliane Grimm from the DepartmentUniversity Hospital Halle (Saale), Halle (Saale), Germany have published the paper: Curse and blessing: upregulation of oncogenes upon treatment with hypomethylating agents in myelodysplastic syndrome, in the Journal: (JOURNAL) of 28/06/2022

SUMMARY

    Received Curse and blessing: upregulation of oncogenes upon treatment with... Grimm and Binder concepts tackling resistance to these drugs. Investigations have to demonstrate whether HMA mediated DNA demethylation and subsequent de-repression of oncogenes may be a universal mechanism which can be recapitulated in the majority of MDS and AML patients, and which targets . . .

     

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