HIGHLIGHTS
- who: Immacolata Pietraforte and collaborators from the Istituto Superiore di Sanitu00e0, Department of Oncology and Molecular Medicine, Rome, Italy Sapienza University of Rome, Roma, Italy have published the research work: CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells, in the Journal: (JOURNAL)
- what: The authors demonstrate that upon binding to self-RNA CXCL4 protects the RNA from enzymatic degradation. The authors show for the first time that CXCL4-RNA complexes circulate in SSc plasma and correlate with both IFN-I and TNF-u03b1. By using monocyte . . .
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