Cxcr3 antagonism of sdf-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension

HIGHLIGHTS

• who: Alexandre Denoyer and collaborators from the UPMC University Paris, Institut de la Vision, UMRS968, Paris, France, INSERM, Paris, France, CNRS, Paris, France, Quinze-Vingts National have published the research work: CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension, in the Journal: (JOURNAL) of February/10,/2012
• what: The authors show that the chemokine CXCL12 its truncated form SDF-1(5-67) and the receptors CXCR4 and CXCR3 are expressed in human glaucomatous trabecular tissue and a human trabecular cell line. In . . .
  

   

  

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