Cyclic di-gmp as an antitoxin regulates bacterial genome stability and antibiotic persistence in biofilms

HIGHLIGHTS

• Who: • August et al. from the Ministry of Education, School and Hospital of Stomatology, Research Institute, Wuhan University, Wuhan, University School of Basic, Wuhan, China have published the research: Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms, in the Journal: (JOURNAL)
• How: An increased propensity of persister formation upon cell ahesion To enhance the clinical relevance of the study the authors employed UPEC the predominant cause of urinary tract infections (UTIs) and responsible for approximately 80% of cases. The results showed that overexpression of mutants lacking the DNA . . .
  

   

  

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