Cyclic gmp-amp synthase (cgas) deletion reduces severity in bilateral nephrectomy mice through changes in neutrophil extracellular traps and mitochondrial respiration

HIGHLIGHTS

  • who: Nattavong Suksawad et al. from the Department of Microbiology, Chulalongkorn University, Bangkok, Thailand have published the paper: Cyclic GMP-AMP Synthase (cGAS) Deletion Reduces Severity in Bilateral Nephrectomy Mice through Changes in Neutrophil Extracellular Traps and Mitochondrial Respiration, in the Journal: Biomedicines 2023, 11, 1208. of 30/09/2021
  • what: This study investigated the role of neutrophils in the BNx-induced gut leakage-associated systemic inflammation mouse model and cultured neutrophils exposed to pathogenic molecules, such as LPS and bacterial cell-free DNA, to mimic the components of bacterial gut leakage. The authors reported . . .

     

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