HIGHLIGHTS
- who: NO et al. from the University of Murcia, Spain have published the Article: Cyclic GMP and PKG Signaling in Heart Failure, in the Journal: (JOURNAL)
SUMMARY
This review focuses on the regulatory mechanisms of cGMP-PKG pathway in heart failure. might depend on the stress conditions and cGMP concentrations (Terasaki and Appleman, 1975; Prigent et_al, 1988; Mery et_al, 1993; Dittrich et_al, 2001; Herring et_al, 2001; Weber et_al, 2017). PDE2 has three splice variants (PDE2A1, 2A2, 2A3), which are differently localized: PDE2A1 in cytoplasm, PDE2A2 in mitochondrial_matrix, and PDE2A3 at membrane (mostly PDE2A3 . . .
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