Cyclin d1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism*

HIGHLIGHTS

  • who: Maofu Fu from the (UNIVERSITY) have published the paper: Cyclin D1 Represses p300 Transactivation through a Cyclin-dependent Kinase-independent Mechanism*, in the Journal: (JOURNAL) of March/23,/2005
  • what: The authors show that cyclin D1 physically interacts with p300 and represses p300 transactivation. Molecular Genetic Phenotype of the Genes Co-regulated by Cyclin D1 and p300 -The current studies demonstrate that cyclin D1 inhibits p300 activity which in turn may regulate a subset of gene functions.
  • how: To determine the genes repressed by cyclin D1 and regulated by p300 at physiological . . .

     

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