Cyclin-dependent kinase 6 (cdk6) as a potent regulator of the ovarian primordial-to-primary follicle transition

HIGHLIGHTS

  • who: December and collaborators from the Biomedicine Discovery Institute, Monash University, Australia have published the research work: Cyclin-dependent kinase 6 (CDK6) as a potent regulator of the ovarian primordial-to-primary follicle transition, in the Journal: (JOURNAL)
  • what: The authors investigated the potential regulatory role of CDK6 in progression of primordial to primary follicle transition using BSJ-03-123 (BSJ), a CDK6-specific degrader. This study showed that CDK6 inhibition can regulate primordial follicle activation, with no effect on the quality and meiotic maturation of oocytes.
  • how: The results showed that diameter . . .

     

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