Cyclin-dependent kinase activity controls the onset of the hcmv lytic cycle

HIGHLIGHTS

• who: from the Children's Hospital, Laboratory for Molecular Biology, Charité Universitätsmedizin Berlin, Berlin, Germany, Free University of Berlin, Faculty of Biology, Chemistry and have published the article: Cyclin-Dependent Kinase Activity Controls the Onset of the HCMV Lytic Cycle, in the Journal: (JOURNAL) of August/11,/2010
• what: The authors show that the block to IE gene expression during S and G2 phase can be overcome by both genotoxic stress and chemical inhibitors of cellular DNA replication pointing to the involvement of checkpointdependent signaling pathways in controlling IE gene repression. The authors show . . .
  

   

  

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