Cyclin-dependent kinase inhibitors in malignant hematopoiesis

HIGHLIGHTS

  • who: Alessia Schirripa from the National Research Council (CNR), Italy University of Salzburg, Austria have published the Article: Cyclin-dependent kinase inhibitors in malignant hematopoiesis, in the Journal: (JOURNAL)
  • future: More studies are required to precisely understand how the p21 Cip1/Waf methylation status interferes with disease progression and if p73 methylation can be used as a marker for the p21Cip1/Waf status.

SUMMARY

    In contrast to INK4 proteins, Cip/Kip proteins have the ability to bind CDK4/6-cyclin D and CDK-cyclin A/B/E complexes. p21Cip1/Waf and . . .

     

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