HIGHLIGHTS
- who: Mohammed E. Abo-El Fetoh from the Department of Pharmacology and Toxicology, Faculty of Pharmacy have published the article: Cyclooxygenase-2 activates EGFR-ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia, in the Journal: (JOURNAL)
- what: This work investigated the potential modulatory effect of inhibition on ADAM-17/EGFR/ERK1/2 axis. The metalloproteinase (ADAMu201117 or TACE) is involved in COXu20112u2011induced ERK1/2 phosphorylation in testosterone (TST)u2011treated animals For this experiment, the upstream activators of ERK1/2 were assessed. In agreement with this concept, this study . . .
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